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2022

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What are the usage and dosage of ferric ammonium citrate effervescent granules?

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Ferric ammonium citrate effervescent granules are used for magnetic resonance abdominal imaging to contrast the digestive tract (stomach, duodenum and jejunum). Then, what are the usage and dosage of ferric ammonium citrate effervescent granules?

The teratogenicity test results of ferric ammonium citrate effervescent particles showed that when pregnant rats and pregnant rabbits were given multiple doses (14 days) of 1200mg/kg and 2000mg/kg respectively, ferric ammonium citrate effervescent particles had no obvious toxicity or teratogenesis in the mother and embryo during organogenesis (6-15 days or 18 days of pregnancy).

The results of multiple administration toxicity test of ferric ammonium citrate effervescent granules showed that the maximum doses of rats and rabbits after multiple administration (14 days) were 1200mg/kg and 2000mg/kg respectively, and no obvious toxic reaction was observed. The only side effect of ferric ammonium citrate Effervescent Granules on dogs after repeated administration (14 days) at a dose of 1200mg/kg was watery stool.

Referring to foreign literature, the acute toxicity test results of ferric ammonium citrate effervescent granules showed that when the maximum dose of ferric ammonium citrate effervescent powder was 2000mg/kg for rats and dogs, except for fecal changes (such as softened stool or watery stool), there was no obvious toxic reaction. No obvious toxic reaction was observed in rats after a single intraperitoneal injection of ferric ammonium citrate effervescent powder 120mg/kg.

Usage and dosage of ferric ammonium citrate effervescent granules: for adults, the dosage is 1 bag, dissolved in 300ml water, and taken orally. If necessary, take 2 bags orally and dissolve in the same amount of water. MRI is usually performed within 20 minutes after taking medicine.

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